Plakophilins, desmogleins, and pemphigus: the tail wagging the dog

The desmosome.

Desmosomes are intercellular junctions that tether intermediate filaments to the plasma membrane. Desmogleins and desmocollins, members of the cadherin superfamily, mediate adhesion at desmosomes. Cytoplasmic components of the desmosome associate with the desmosomal cadherin tails through a series of protein interactions, which serve to recruit intermediate filaments to sites of desmosome assem...

Behavioural responses of Canis familiaris to different tail lengths of a remotely-controlled life-size

The tail of dogs and allies (Canidae) is important for intraspecific communication. We used a life-sized dog model and varied the tail length and motion as an experimental method of examining effects of tail-docking on intraspecific signaling in domestic dogs, Canis familiaris. We videotaped interactions of 492 off-leash dogs and quantified size and behaviour of approaching dogs to the model’s ...

The tail is wagging the dog: body culture, classification and the paralympic movement

Tail Wagging the Dog: Is China’s Mto the Driving Force behind Methanol Pricing?

Pemphigus erythematosus and cutaneous epitheliotropic lymphoma in a Labrador Retriever dog

Background: Paraneoplastic pemphigus is an autoimmune blistering skin disease associated with concurrent neoplasia that is rarely observed in veterinary medicine. Case description: This case report presents a ten-year-old female Labrador Retriever dog with generalized seborrhea and alopecic, crusting and ulcerative lesions in the periocular and perioral regions...